Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Public comment period · §2

Draft policy on the register of members and reviewers — submissions

The 13 submissions received, published in full with declared interests and secretariat responses.

Document identifier
CEI-CP-021/2
Series
Public comment period
Version
1.0
Published
10 Jul 2024
Last reviewed
10 Jul 2024
Next review
10 Jul 2025
Identifier
10.71829/cei.cp.21
Certainty
Not rated
Cycle
2024 Q2
Window
01 May 2024 – 30 Jun 2024
Status
Closed
Submissions
13

§2Submissions and responses

13 submissions were received. Each is published in full below with its declared interest, the secretariat response and the disposition. The Institute publishes submissions it did not accept in the same form as those it did.

Professor Bartolomeu Nkosi-Lindegaard, PhD Professor of Regulatory Science · submitting on regulatory science
DRAFT-PEOPLE-REGIS/001 received 04 May 2024

Independence is asserted and the mechanism securing it is not described

The respondent has read policy on the register of members and reviewers in draft and makes one submission.

The document states that sponsorship does not influence assessment. It does not describe what prevents it from doing so, and an assertion without a mechanism is not verifiable.

The respondent proposes that the separation between the party accepting funding and the party making assessments be described in operational terms.

Declared interest. Is a member of the Institute's external reviewer register but did not review the document under consultation.
Secretariat responseAccepted16 Jul 2024

The secretariat accepts this submission.

The governance document now describes the separation in operational terms: who accepts funding, who makes assessments, that the two sets do not overlap, and that assessment staff are not informed of placement decisions before publication.

Dr Beatrijs Hazelrigg, MD, MSc University department of public health · submitting on health-technology assessment
DRAFT-PEOPLE-REGIS/002 received 06 May 2024

Assessment committee meetings are held in private

The respondent submits on policy on the register of members and reviewers. Governance documents are read by very few people and relied on by everyone who reads anything else the Institute publishes.

Comparable bodies admit observers to at least part of a meeting. The document does not say whether the Institute has considered doing so.

The respondent proposes that part of each meeting be open, or that the reason for holding meetings in private be stated.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseNoted, no amendment15 Jul 2024

The secretariat notes this submission and states the position rather than changing it.

Meetings are held in private and the reason is now stated: the committee assesses draft ratings that will change before publication, and an observed deliberation on a draft rating tends to produce a published deliberation rather than a candid one. The minutes and the dissenting positions are published.

Dr Vasilisa Sandringham-Adu, MD, MPH Primary-care research network · submitting on public health
DRAFT-PEOPLE-REGIS/003 received 11 May 2024

What the site collects about a reader is not stated in terms a reader can check

The respondent notes that policy on the register of members and reviewers governs situations that will arise rarely and matter greatly when they do, and submits accordingly.

The respondent states that a body assessing evidence should be checkable in its own conduct, and that a general privacy statement does not permit a reader to verify what is collected.

The respondent proposes that the statement enumerate what is collected and that it be verifiable from the page itself.

The respondent has read submission 002 and asks that this submission be considered with it.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseAccepted26 Jul 2024

The secretariat accepts this submission. An unverifiable statement about data is exactly the kind of claim the Institute declines to accept from others.

The statement now enumerates what is collected and what is not, and is written so that a reader can verify it from the page source, which is the only form of the statement that can be checked without trusting the Institute.

Dr Vasilisa Immelmann, PharmD, PhD Health-technology assessment agency · submitting on regulatory science
DRAFT-PEOPLE-REGIS/004 received 14 May 2024

Recusal should follow automatically from any declared financial interest

Having read the draft of policy on the register of members and reviewers, the respondent puts one point to the secretariat.

The respondent states that case-by-case recusal decisions require the body making them to judge its own members, and that an automatic rule removes the judgement and with it the appearance of partiality.

The respondent proposes automatic recusal on any declared financial interest in a named company.

The respondent has read submission 003 and puts a further matter to the secretariat.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseNot accepted15 Jul 2024

The secretariat does not accept this submission. An automatic rule of that breadth would recuse most of the people competent to assess the evidence, and the Institute would be left with assessors chosen for their distance from the field.

Recusal remains determined against the specific document, with the decision, its reasons and the person recused published in the document front matter. The submission is published in full because it identifies a genuine tension the Institute has resolved in one direction rather than removed.

Quentin Whitmarsh-Obi, MSc (Clinical Pharmacy) Regional hospital pharmacy department · submitting on medicines information
DRAFT-PEOPLE-REGIS/005 received 18 May 2024

The search date is not on the face of the document

The draft of policy on the register of members and reviewers was read for what it obliges the Institute to do rather than for what it says the Institute intends.

The draft carries a publication date and a review date but not the date on which the evidence was last searched. Those are three different dates and only the third tells a reader how current the assessment is. A document published in one quarter may rest on a search run two quarters earlier, and nothing on the page allows that gap to be measured.

The respondent proposes that the search date be printed adjacent to every certainty rating rather than in the methods section, on the ground that a reader who acts on a rating is unlikely to have read the methods section first.

This submission should be read alongside submission 004, which arises on the same draft.

Declared interest. Has received travel support to attend a scientific meeting from a manufacturer of a compound named in the draft.
Secretariat responseAccepted15 Jul 2024

The secretariat accepts this submission. The distinction between publication, review and search dates is real and the draft did not make it visible where it mattered.

The search date is now printed adjacent to every certainty rating and is carried in the document metadata, so that the interval between the search and the reading is visible without reference to the methods section.

Kolawole Oppenheimer-Ade, BA Primary-care research network · submitting on patient and public involvement
DRAFT-PEOPLE-REGIS/006 received 23 May 2024

The Institute publishes no telephone number and no messaging channel

The respondent’s comment on policy on the register of members and reviewers is made from the standpoint of a person who might be affected by a decision taken under it.

The respondent states that a body inviting submissions ordinarily provides a channel for questions about the process, and that the written address alone is a high barrier for a first-time respondent.

The respondent asks that a route for procedural questions be provided.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseNoted, no amendment17 Jul 2024

The secretariat notes this submission. The written route is the only route and that is a deliberate constitutional position rather than an omission.

No amendment arises. The Institute holds no telephone number and uses no messaging channel, because a submission made in writing is a document that can be published with its response and an oral exchange is not. Guidance on making a submission has been expanded so that the written route requires no prior enquiry to use.

Dr Prosper Vercingetorix, MD, MSc University department of public health · submitting on health-technology assessment
DRAFT-PEOPLE-REGIS/007 received 24 May 2024

No period is stated within which a submission will be answered

The respondent has read policy on the register of members and reviewers and submits on a matter of presentation.

A respondent who has made a submission has no basis for knowing whether silence means the submission is being considered or has been lost.

The respondent proposes a stated period, with an acknowledgement on receipt and a substantive response within it.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted19 Jul 2024

The secretariat accepts this submission.

Receipt is acknowledged within five working days and a substantive response is published within eight weeks of the window closing. Where that period cannot be met the reason is published in its place.

Vittoria Ylönen, MSc (Epidemiology) Health-technology assessment agency · submitting on public health
DRAFT-PEOPLE-REGIS/008 received 28 May 2024

Declared interests should appear on the document rather than on a separate page

The respondent read policy on the register of members and reviewers in draft and has confined this submission to one clause.

The draft links to a central conflicts register. The respondent argues that a reader assessing whether to rely on a particular document should not have to leave it to find out who assessed it and what they declared.

The respondent proposes that the interests of every named contributor to a document be printed on that document.

The respondent’s submission overlaps with submission 006 and was prepared without sight of it.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseNoted, no amendment02 Aug 2024

The secretariat notes this submission and records that the draft already provides for it, which the respondent could reasonably have missed because the provision sits in an appendix.

Every document carries the declared interests of its named contributors in its front matter, and the central register exists so that a reader can see a person across all documents rather than one at a time. No amendment arises; the provision has been moved from the appendix into the body of the methodology document so that it is findable.

Kolawole Jankowiak-Osei, BSc Primary-care research network · submitting on patient and public involvement
DRAFT-PEOPLE-REGIS/009 received 28 May 2024

The position of a contributor who withdraws consent is not stated

The respondent submits on policy on the register of members and reviewers, on a matter that is not specific to this draft but is visible in it.

The respondent states that consent to be named is obtained at submission and that the policy is silent on what happens if it is later withdrawn, which leaves both the Institute and the contributor without a rule.

The respondent proposes that the position be stated in advance and be the same for everyone.

Declared interest. Has used a compound in the class under assessment under prescription. Declared at the Institute's request; the Institute regards a lived-experience declaration as an interest and not as a disqualification.
Secretariat responseAccepted22 Jul 2024

The secretariat accepts this submission. A rule made at the point of the first withdrawal is a rule made about a particular person.

The policy now states that a contributor may withdraw from the register at any time and that the register entry is removed, while a signed submission already published remains published, because the consultation record is a record of what was said and by whom. The position is stated at the point consent is given.

Dr Georgiana Mountstephen, MD, FFPH University department of public health · submitting on public health
DRAFT-PEOPLE-REGIS/010 received 30 May 2024

Whether external reviewers are paid is not stated

This submission concerns the draft of policy on the register of members and reviewers. The respondent has served on committees operating comparable regimes and the observation draws on that.

The respondent states that payment or its absence bears on who is able to review and on what the Institute may expect of them, and that the policy does not address it.

The respondent proposes that the position be stated and that any payment be disclosed at the level of the individual document.

The respondent notes submission 009 above and does not repeat the ground it covers.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted19 Jul 2024

The secretariat accepts this submission. Payment is an interest and the policy treats interests as facts to be published.

The policy now states whether external review is remunerated, records any payment made in respect of a document in that document's front matter, and treats a payment received from the Institute as a declarable interest in the same way as any other.

Dr Evander Ashworth-Danquah, PharmD, MSc Health-technology assessment agency · submitting on health-technology assessment
DRAFT-PEOPLE-REGIS/011 received 10 Jun 2024

The secretariat answers submissions and is not itself named

This is a submission on policy on the register of members and reviewers, from a respondent representing readers rather than practitioners.

The respondent states that responses are attributed to the secretariat as a body, and that a reader cannot tell who wrote a response or whether that person had a relevant interest.

The respondent proposes that responses be signed individually.

Declared interest. Holds a personal shareholding, below the Institute's materiality threshold, in a diversified fund with pharmaceutical sector exposure. No direct holding in any named company.
Secretariat responseAccepted in part12 Jul 2024

The secretariat accepts this submission in part. Responses are attributed to the named members of the secretariat responsible for the document rather than to individuals per response, and the interests of those members are published.

Every comment period now names the secretariat members responsible for it, with their declared interests, in the consultation front matter, so that the responses can be read against the interests of the people who wrote them.

Dr Quentin Enthoven, MD, FFPH University department of public health · submitting on public health
DRAFT-PEOPLE-REGIS/012 received 10 Jun 2024

A party that is assessed and also sponsors should be disclosed on its own assessment

The respondent read policy on the register of members and reviewers in draft. The point applies to it and to the series generally.

Disclosure on the funding page is necessary and is not sufficient. The reader who most needs to know is the one reading that party’s assessment, and that reader has no reason to visit the funding page.

The respondent proposes that the disclosure appear on the assessment itself, in the same visual weight as the assessment summary.

This submission should be read alongside submission 009, which arises on the same draft.

Declared interest. No financial or non-financial interest to declare in relation to the subject of this consultation.
Secretariat responseAccepted26 Jul 2024

The secretariat accepts this submission without qualification. It was a real defect.

The disclosure now appears as a numbered section on the dossier of any assessed party that sponsors the site, as well as on the funding page.

Wilhelmina Erlingsson, BSc Primary-care research network · submitting on patient and public involvement
DRAFT-PEOPLE-REGIS/013 received 12 Jun 2024

A submission the Institute declines to publish leaves no trace

This submission addresses policy on the register of members and reviewers from the standpoint of an outside body that would have to rely on it.

The policy permits a submission to be declined where it is abusive or names an individual. Nothing records that a submission was received and declined, so the published set cannot be distinguished from the received set.

The respondent proposes a count of declined submissions with the ground for each.

Declared interest. Has used a compound in the class under assessment under prescription. Declared at the Institute's request; the Institute regards a lived-experience declaration as an interest and not as a disqualification.
Secretariat responseNoted, no amendment31 Jul 2024

The secretariat notes this submission and has adopted part of it.

The number of submissions declined and the ground for each is now published on the disposition page of the consultation concerned. The submissions themselves are not published, for the reasons that caused them to be declined.

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. International Organization for Standardization. ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories. ISO/IEC Standard 2017;3rd edition. identifier not held by the Institute

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.