Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Public comment period · §3

Draft indication set and anchor outcomes — disposition

The disposition of every submission and the amendments that resulted.

Document identifier
CEI-CP-024/3
Series
Public comment period
Version
1.0
Published
08 Oct 2023
Last reviewed
08 Oct 2023
Next review
08 Oct 2024
Identifier
10.71829/cei.cp.24
Certainty
Not rated
Cycle
2023 Q3
Window
09 Aug 2023 – 23 Sep 2023
Status
Closed
Submissions
15

§3Disposition and amendments

§3.1Disposition table

Table 1. Every submission with its disposition. Each row links to the submission in full.

ReferenceRespondentPoint raisedDisposition
DRAFT-INDICATION-S/001Quentin Whitmarsh-ObiThe front-matter summary describes the finding without stating itAccepted
DRAFT-INDICATION-S/002Dr Melisande Kirkpatrick-OlaFour dates are given and their relation is not explainedAccepted
DRAFT-INDICATION-S/003Dr Frideswide NordhagenA printed copy loses the information that makes it checkableAccepted
DRAFT-INDICATION-S/004Dr Adaeze Underhill-OkaforA fixed section structure will force empty sectionsAccepted in part
DRAFT-INDICATION-S/005Dr Hyacinth Drakeford-AmadiA printed copy loses the document identifierAccepted
DRAFT-INDICATION-S/006Dr Vasilisa ImmelmannThe identifier encodes the document type, which is a property that can changeAccepted
DRAFT-INDICATION-S/007Vittoria YlönenThe document set should be published in translationNot accepted
DRAFT-INDICATION-S/008Anselm MountstephenA superseded version should remain reachable from the version that replaced itNoted, no amendment
DRAFT-INDICATION-S/009Eamon Sandringham-AduThe registry is published only as pages and not in a form that can be processedAccepted
DRAFT-INDICATION-S/010Ivo MountstephenThe same quantity is presented differently in two seriesAccepted
DRAFT-INDICATION-S/011Dr Fenella Steenkamp-FerreiraThe default ordering of a comparison table carries an implicationAccepted
DRAFT-INDICATION-S/012Dr Yusuf Whitmarsh-ObiThe index shows ratings without the reasons behind themAccepted
DRAFT-INDICATION-S/013Dr Marisol Dunmore-EkpoA section with nothing in it is emitted with a heading and a sentence saying soAccepted
DRAFT-INDICATION-S/014Dr Oisín RautavaaraPoint estimates are given without an intervalAccepted in part
DRAFT-INDICATION-S/015Dr Vittoria QuintanilhaA document is split across parts at a point that separates a claim from its supportAccepted in part
15 submissions in total.

§3.2Summary by disposition

Table 2. Counts by disposition, with the meaning of each.

DispositionCountMeaning
Accepted10The submission is accepted and the draft is amended as proposed. The amendment is recorded in the amendment log of the document it changed and is traceable to the numbered submission.
Accepted in part3Part of the submission is accepted and part is not. The secretariat response states which part is which and on what ground the remainder was declined.
Noted, no amendment1The submission raises a point the Institute accepts but that does not require a change to the draft, most often because the draft already states it elsewhere. The location is given in the response.
Not accepted1The submission is not accepted. The secretariat response gives the reason. A submission that is not accepted remains published in full; the Institute does not remove a submission because it disagrees with it.

§3.3Resulting amendments

  1. The front-matter summary describes the finding without stating it — arising from DRAFT-INDICATION-S/001. The front-matter summary now carries the principal estimate with its interval and its certainty rating, so that the three travel together wherever the summary is quoted.
  2. Four dates are given and their relation is not explained — arising from DRAFT-INDICATION-S/002. The metadata block now carries a one-line gloss stating that the search date determines how current the evidence assessment is, and that a later review date without a later search date means the document was checked and not re-searched.
  3. A printed copy loses the information that makes it checkable — arising from DRAFT-INDICATION-S/003. The print stylesheet now carries the identifier, version, publication date and retrieval date on every page, expands link destinations into the text, and prints the full reference list rather than a link to it.
  4. A fixed section structure will force empty sections — arising from DRAFT-INDICATION-S/004. A section with nothing to report now states that fact and the reason in a fixed form, rather than being omitted or left blank, so that a reader can tell the difference between an absence of evidence and an absence of effort.
  5. A printed copy loses the document identifier — arising from DRAFT-INDICATION-S/005. The print stylesheet now carries the document identifier, the version, the publication date and the address in a footer on every printed page.
  6. The identifier encodes the document type, which is a property that can change — arising from DRAFT-INDICATION-S/006. The identifier is retained in its present form and a standing commitment is published that no identifier will be reassigned. A document that moves between series keeps the identifier it was issued with, and the type segment is documented as historical rather…
  7. The registry is published only as pages and not in a form that can be processed — arising from DRAFT-INDICATION-S/009. The registry fields are now emitted in a structured form alongside the rendered pages, carrying the identifier, series, type, version, dates, certainty rating and status for every document, and the structured record is regenerated with the site so that it…
  8. The same quantity is presented differently in two series — arising from DRAFT-INDICATION-S/010. Certainty ratings are now presented identically across every series, using the same badge, the same wording and the same accompanying formulation, and the presentation is specified in the series structure document rather than left to each series.
  9. The default ordering of a comparison table carries an implication — arising from DRAFT-INDICATION-S/011. The default ordering is now alphabetical, a standing statement above every comparison table records that the ordering is not a ranking, and the sort state is reset on reload so that a shared link does not carry an ordering the sender chose.
  10. The index shows ratings without the reasons behind them — arising from DRAFT-INDICATION-S/012. Every index row now carries the downgrade domains alongside the rating, and the index can be filtered by domain so that a reader can see, for example, every outcome downgraded for imprecision across the document set.
  11. A section with nothing in it is emitted with a heading and a sentence saying so — arising from DRAFT-INDICATION-S/013. A section with no content is now folded into its parent as a single recorded line. The fact of the absence is preserved, because an absent section and an absent statement are different, and the heading is not.
  12. Point estimates are given without an interval — arising from DRAFT-INDICATION-S/014. Every estimate now carries its interval where the source reported one, and where it did not, the estimate is annotated as reported without an interval rather than left to appear as a precise figure.
  13. A document is split across parts at a point that separates a claim from its support — arising from DRAFT-INDICATION-S/015. Every part now carries the certainty rating in its own metadata header and repeats it beside any estimate it reproduces, so that no page presents an estimate without its rating.

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. International Organization for Standardization. ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories. ISO/IEC Standard 2017;3rd edition. identifier not held by the Institute

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

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